In-depth guide

UPDATED FEB 2026

Part of the Testosterone Therapy investigation

The short answer

AbbVie's AndroGel was the #1 selling testosterone gel in the U.S. with over $1 billion in annual sales at peak. AbbVie is accused of marketing AndroGel to men with normal age-related hormone decline without adequate cardiovascular warnings.

MDL 2545 in Chicago has processed over 10,000 AndroGel cases. AbbVie reportedly settled its MDL inventory for an estimated $250M–$500M (confidential). New cases are still being filed.

People's Justice Research TeamUpdated February 23, 2026Fact-checked

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AbbVie Inc. manufactures AndroGel 1% and AndroGel 1.62% — prescription testosterone gels applied to the skin daily. At its commercial peak around 2012–2014, AndroGel generated over $1 billion annually in U.S. sales, fueled by a massive "Low T" direct-to-consumer advertising campaign that encouraged men to self-diagnose testosterone deficiency based on symptoms of normal aging.

Clinical research — including a 2013 JAMA study of 55,000 VA patients and the FDA's own 2014 safety review — found significant cardiovascular risk in AndroGel users. The FDA issued a black box warning in 2015. MDL 2545 in the Northern District of Illinois consolidated over 10,000 cases against AbbVie alone. After multiple bellwether trials with mixed results, AbbVie reached a confidential global settlement estimated at $250M–$500M for its MDL inventory.

The full investigation

Part of the Testosterone Therapy Investigation