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The C8 Science Panel and Ulcerative Colitis
The C8 Science Panel — the independent scientific body funded by DuPont's 2004 settlement to study the health effects of PFOA exposure in the Mid-Ohio Valley — published its findings in 2012 after studying over 69,000 exposed individuals. The panel designated six conditions as having a 'probable link' to PFOA exposure: kidney cancer, testicular cancer, thyroid disease, ulcerative colitis, high cholesterol, and pregnancy-induced hypertension. Ulcerative colitis was identified based on a statistically significant elevated incidence rate in PFOA-exposed community members compared to unexposed controls, and on biological mechanisms involving PFAS disruption of the intestinal epithelial barrier and immune regulation in the gut. An Emory University study subsequently confirmed the PFAS-ulcerative colitis association in additional cohorts. In MDL 2873, ulcerative colitis is a recognized personal injury category.
What Documentation Is Needed for Ulcerative Colitis PFAS Claims
To file a PFAS ulcerative colitis claim, you need: (1) A confirmed diagnosis of ulcerative colitis by a gastroenterologist, supported by colonoscopy findings and pathology — Crohn's disease and non-specific colitis diagnoses may also be considered but are not as directly tied to the PFAS epidemiological evidence; (2) Documentation of PFAS-contaminated water exposure prior to diagnosis; (3) A medically plausible timeline — UC linked to PFAS exposure should have developed during or after a period of sustained PFAS water consumption. Ulcerative colitis requires ongoing treatment — mesalamine, immunosuppressants, biologics (infliximab, vedolizumab), or in severe cases colectomy — creating substantial lifetime medical damages that support meaningful compensation even in the absence of a cancer diagnosis.
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Related Guides
- AFFF Firefighter PFAS Exposure LawsuitFirefighters — both military and civilian — who worked with AFFF aqueous film-forming foam face the highest documented PFAS body burdens of any occupational group. AFFF contains PFOS and PFOA at concentrations orders of magnitude higher than contaminated drinking water. Firefighters with kidney cancer, testicular cancer, or thyroid disease following AFFF exposure have strong individual claims in MDL 2873.
- PFAS Biosolids Farm Contamination LawsuitPFAS-contaminated biosolids (sewage sludge) spread as agricultural fertilizer have contaminated private wells and farmland across the United States — a largely invisible exposure pathway that is only now reaching litigation. Affected farmers, rural homeowners, and farmworkers in Maine, Iowa, Michigan, and Texas have active claims. This is one of the least-covered and fastest-growing fronts in PFAS litigation.
- GenX Chemicals Chemours Lawsuit — Cape Fear RiverChemours Company — a DuPont spinoff — has discharged GenX chemicals (HFPO-DA) from its Fayetteville Works facility in Bladen County, North Carolina into the Cape Fear River since 2006. Wilmington-area residents who drank Cape Fear River water have been exposed to GenX and other PFAS at concentrations far above EPA health advisory levels. This is among the largest active industrial PFAS contamination zones in the eastern United States, and it is significantly underserved by legal content.
- PFAS Kidney Cancer LawsuitKidney cancer (renal cell carcinoma) is the MDL 2873 Tier 1 bellwether injury — the PFAS-linked condition with the strongest and most consistent epidemiological association. The IARC classified PFOA as a Group 1 known human carcinogen for kidney cancer in 2023. Individuals who developed kidney cancer after sustained PFAS exposure through drinking water have among the strongest claims in PFAS litigation.
- Military Base PFAS Contamination LawsuitMore than 700 U.S. military installations have confirmed PFAS contamination from decades of AFFF firefighting foam use. Veterans, active-duty service members, military families, and civilian base employees who lived or worked on contaminated installations and developed kidney cancer, testicular cancer, or thyroid disease may have substantial legal claims. The DoD has confirmed contamination at bases in all 50 states.
- Military Bases with PFAS Contamination — Complete ListThe Department of Defense has confirmed PFAS contamination at more than 700 U.S. military installations as of 2026. This page provides a state-by-state summary of confirmed contaminated bases and the communities affected. If you lived or served at a contaminated installation and developed a qualifying health condition, contact a PFAS attorney to evaluate your claim.
- PFAS Settlement Amounts Per PersonThe $12.5 billion 3M settlement and $1.185 billion DuPont/Chemours/Corteva settlement compensate water utilities — not individuals. Individual PFAS personal injury settlement amounts depend on injury category, exposure documentation, and MDL 2873 bellwether trial outcomes. Kidney and testicular cancer claims are expected to produce the highest individual recoveries, estimated at $300,000 to $600,000 or more.
- PFAS Lawsuit Statute of Limitations by StateThe statute of limitations for PFAS personal injury claims is typically 2 to 3 years from diagnosis or from when you discovered the PFAS-illness connection. Because military and industrial PFAS contamination was not publicly disclosed until 2016–2020 in most communities, courts have been receptive to delayed discovery arguments. Act now — deadlines are real, and missing them permanently bars your claim.
- PFAS Testicular Cancer LawsuitTesticular cancer is an MDL 2873 Tier 1 injury category with one of the strongest epidemiological links to PFAS — particularly PFOS exposure. The cancer predominantly affects younger men (age 15–35), meaning veterans and firefighters who developed testicular cancer after PFAS exposure at military installations often carry decades of lost earnings and quality-of-life damages. Claims in MDL 2873 are active and advancing toward bellwether trials in 2026.
- PFAS Thyroid Disease and Thyroid Cancer LawsuitPFAS disrupt thyroid hormone signaling by mimicking and competing with thyroid hormones at receptor and transport protein binding sites. Women are disproportionately affected. Diagnosed thyroid disease requiring medication (hypothyroidism, hyperthyroidism, Hashimoto's thyroiditis) and thyroid cancer are recognized injury categories in MDL 2873. A 2018 Mount Sinai study found significantly elevated thyroid cancer risk with higher serum PFAS concentrations.
- PFAS Drinking Water Contamination LawsuitPFAS-contaminated municipal water systems and private wells have exposed millions of Americans to dangerous concentrations of forever chemicals. Residents who drank contaminated tap water for years and developed kidney cancer, testicular cancer, or thyroid disease have individual claims in MDL 2873. You do not need to have lived near a military base — industrial and agricultural PFAS sources have contaminated water supplies across the country.
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